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Immobilization of Jagged1 Enhances Vascular Smooth Muscle Cells Maturation by Activating the Notch Pathway

In Notch signaling, the Jagged1-Notch3 ligand-receptor pairing is implicated for regulating the phenotype maturity of vascular smooth muscle cells. However, less is known about the role of Jagged1 presentation strategy in this regulation. In this study, we used bead-immobilized Jagged1 to direct phe...

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Detalles Bibliográficos
Autores principales: Zohorsky, Kathleen, Lin, Shigang, Mequanint, Kibret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391929/
https://www.ncbi.nlm.nih.gov/pubmed/34440858
http://dx.doi.org/10.3390/cells10082089