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Heterogeneity of Hepatic Stellate Cells in Fibrogenesis of the Liver: Insights from Single-Cell Transcriptomic Analysis in Liver Injury

Background & Aims: Liver fibrosis is a pathological healing process resulting from hepatic stellate cell (HSC) activation and the generation of myofibroblasts from activated HSCs. The precise underlying mechanisms of liver fibrogenesis are still largely vague due to lack of understanding the fun...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjun, Conway, Simon J., Liu, Ying, Snider, Paige, Chen, Hanying, Gao, Hongyu, Liu, Yunlong, Isidan, Kadir, Lopez, Kevin J., Campana, Gonzalo, Li, Ping, Ekser, Burcin, Francis, Heather, Shou, Weinian, Kubal, Chandrashekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391930/
https://www.ncbi.nlm.nih.gov/pubmed/34440898
http://dx.doi.org/10.3390/cells10082129