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RARβ Expression in Keratinocytes from Potentially Malignant Oral Lesions: The Functional Consequences of Re-Expression by De-Methylating Agents

SIMPLE SUMMARY: Patients may develop white or red patches of the lining of the mouth with an increased risk of developing oral cancer. Treatment with Vitamin A derivatives (retinoids) results in some improvement in these lesions, but this is not maintained, and there are side effects. We know that t...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Raghu, Crane, Hannah L., Daigneault, Marc, Padam, Kanaka Sai Ram, Hunter, Keith D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391937/
https://www.ncbi.nlm.nih.gov/pubmed/34439217
http://dx.doi.org/10.3390/cancers13164064