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Polycationic Monomeric and Homodimeric Asymmetric Monomethine Cyanine Dyes with Hydroxypropyl Functionality—Strong Affinity Nucleic Acids Binders

New analogs of the commercial asymmetric monomethine cyanine dyes thiazole orange (TO) and thiazole orange homodimer (TOTO) with hydroxypropyl functionality were synthesized and their properties in the presence of different nucleic acids were studied. The novel compounds showed strong, micromolar an...

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Detalles Bibliográficos
Autores principales: Mikulin, Ivana, Ljubić, Ivana, Piantanida, Ivo, Vasilev, Aleksey, Mondeshki, Mihail, Kandinska, Meglena, Uzelac, Lidija, Martin-Kleiner, Irena, Kralj, Marijeta, Tumir, Lidija-Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391988/
https://www.ncbi.nlm.nih.gov/pubmed/34439741
http://dx.doi.org/10.3390/biom11081075