Synuclein Family Members Prevent Membrane Damage by Counteracting α-Synuclein Aggregation

The 140 amino acid protein α-synuclein (αS) is an intrinsically disordered protein (IDP) with various roles and locations in healthy neurons that plays a key role in Parkinson’s disease (PD). Contact with biomembranes can lead to α-helical conformations, but can also act as s seeding event for aggre...

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Detalles Bibliográficos
Autores principales: Scheibe, Christian, Karreman, Christiaan, Schildknecht, Stefan, Leist, Marcel, Hauser, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392020/
https://www.ncbi.nlm.nih.gov/pubmed/34439733
http://dx.doi.org/10.3390/biom11081067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392020/
https://www.ncbi.nlm.nih.gov/pubmed/34439733
http://dx.doi.org/10.3390/biom11081067

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