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Impact of a Single Nucleotide Change or Non-Nucleoside Modifications in G-Rich Region on the Quadruplex–Duplex Hybrid Formation

In this paper, a method to discriminate between two target RNA sequences that differ by one nucleotide only is presented. The method relies on the formation of alternative structures, i.e., quadruplex–duplex hybrid (QDH) and duplex with dangling ends (Dss), after hybridization of DNA or RNA G-rich o...

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Detalles Bibliográficos
Autores principales: Gudanis, Dorota, Zielińska, Karolina, Baranowski, Daniel, Kierzek, Ryszard, Kozłowski, Piotr, Gdaniec, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392043/
https://www.ncbi.nlm.nih.gov/pubmed/34439902
http://dx.doi.org/10.3390/biom11081236