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Proton-Sensing GPCRs in Health and Disease

The group of proton-sensing G-protein coupled receptors (GPCRs) consists of the four receptors GPR4, TDAG8 (GPR65), OGR1 (GPR68), and G2A (GPR132). These receptors are cellular sensors of acidification, a property that has been attributed to the presence of crucial histidine residues. However, the p...

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Detalles Bibliográficos
Autores principales: Sisignano, Marco, Fischer, Michael J. M., Geisslinger, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392051/
https://www.ncbi.nlm.nih.gov/pubmed/34440817
http://dx.doi.org/10.3390/cells10082050