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Interleukin-30 Suppresses Not Only CD4(+) T Cells but Also Regulatory T Cells in Murine Primary Biliary Cholangitis
Primary biliary cholangitis (PBC) is a chronic liver autoimmune disease with augmented T helper (Th) 1 and corresponding cytokine IFN-γ immune responses. Using 2-octynoic acid (2-OA) coupled to OVA (2-OA-OVA)-induced mouse models of autoimmune cholangitis (inducible chemical xenobiotic models of PBC...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392158/ https://www.ncbi.nlm.nih.gov/pubmed/34440235 http://dx.doi.org/10.3390/biomedicines9081031 |