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Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in lupus patients

Responses to vaccination and to diseases vary widely across individuals, which may be partly due to baseline immune variations. Identifying such baseline predictors of immune responses and their biological basis are of broad interest given their potential importance for cancer immunotherapy, disease...

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Detalles Bibliográficos
Autores principales: Kotliarov, Yuri, Sparks, Rachel, Martins, Andrew J., Mulè, Matthew P., Lu, Yong, Goswami, Meghali, Kardava, Lela, Banchereau, Romain, Pascual, Virginia, Biancotto, Angelique, Chen, Jinguo, Schwartzberg, Pamela L., Bansal, Neha, Liu, Candace C., Cheung, Foo, Moir, Susan, Tsang, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392163/
https://www.ncbi.nlm.nih.gov/pubmed/32094927
http://dx.doi.org/10.1038/s41591-020-0769-8