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Interferon-β Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease

Interferon (IFN)-β is a popular therapy for multiple sclerosis (MS). However, 25–40% of patients are nonresponsive to this therapy, and it worsens neuromyelitis optica (NMO), another neuroinflammatory disease. We previously identified, in both NMO patients and in mice, that IFN-β treatment had infla...

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Detalles Bibliográficos
Autores principales: Agasing, Agnieshka, Quinn, James L., Kumar, Gaurav, Axtell, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392231/
https://www.ncbi.nlm.nih.gov/pubmed/34440908
http://dx.doi.org/10.3390/cells10082139