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Technical Evaluation of the COBAS EGFR Semiquantitative Index (SQI) for Plasma cfDNA Testing in NSCLC Patients with EGFR Exon 19 Deletions

The cobas(®) EGFR Test provides a semiquantitative index (SQI) that reflects the proportion of mutated versus wild-type copies of the EGFR gene in plasma. The significance of SQI as an indirect measure of the variant allele frequency (VAF) or mutated copies/mL remains unclear. The aim of this study...

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Detalles Bibliográficos
Autores principales: González de Aledo-Castillo, José Manuel, Serhir-Sgheiri, Samira, Calbet-Llopart, Neus, Arcocha, Ainara, Jares, Pedro, Reguart, Noemí, Puig-Butillé, Joan Antón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392299/
https://www.ncbi.nlm.nih.gov/pubmed/34441254
http://dx.doi.org/10.3390/diagnostics11081319