Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage

Niemann-Pick type C disease (NPCD) is a lysosomal storage disorder caused by mutations in the NPC1 gene. The most affected tissues are the central nervous system and liver, and while significant efforts have been made to understand its neurological component, the pathophysiology of the liver damage...

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Detalles Bibliográficos
Autores principales: Balboa, Elisa, Marín, Tamara, Oyarzún, Juan Esteban, Contreras, Pablo S., Hardt, Robert, van den Bosch, Thea, Alvarez, Alejandra R., Rebolledo-Jaramillo, Boris, Klein, Andres D., Winter, Dominic, Zanlungo, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392304/
https://www.ncbi.nlm.nih.gov/pubmed/34440927
http://dx.doi.org/10.3390/cells10082159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392304/
https://www.ncbi.nlm.nih.gov/pubmed/34440927
http://dx.doi.org/10.3390/cells10082159

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