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The Ups and Downs of STAT Inhibition in Acute Myeloid Leukemia

Aberrant Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling is implicated in the pathogenesis of acute myeloid leukemia (AML), a highly heterogeneous hematopoietic malignancy. The management of AML is complex and despite impressive efforts into better understanding it...

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Detalles Bibliográficos
Autores principales: Moser, Bernhard, Edtmayer, Sophie, Witalisz-Siepracka, Agnieszka, Stoiber, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392322/
https://www.ncbi.nlm.nih.gov/pubmed/34440253
http://dx.doi.org/10.3390/biomedicines9081051