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The Parkinson’s Disease-Associated Protein DJ-1 Protects Dictyostelium Cells from AMPK-Dependent Outcomes of Oxidative Stress

Mitochondrial dysfunction has been implicated in the pathology of Parkinson’s disease (PD). In Dictyostelium discoideum, strains with mitochondrial dysfunction present consistent, AMPK-dependent phenotypes. This provides an opportunity to investigate if the loss of function of specific PD-associated...

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Detalles Bibliográficos
Autores principales: Chen, Suwei, Annesley, Sarah J., Jasim, Rasha A. F., Fisher, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392454/
https://www.ncbi.nlm.nih.gov/pubmed/34440642
http://dx.doi.org/10.3390/cells10081874