Variants Affecting the C-Terminal Tail of UNC93B1 Are Not a Common Risk Factor for Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a heterogeneous multifactorial disease. Upregulated TLR7 signaling is a known risk factor for SLE. Recently, it was shown that specific genetic variants in UNC93B1 affect the physiological regulation of TLR7 signaling and cause characteristic autoimmune phenotyp...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiener, Sarah, Ribi, Camillo, Keller, Irene, Chizzolini, Carlo, Trendelenburg, Marten, Huynh-Do, Uyen, von Kempis, Johannes, Leeb, Tosso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392493/
https://www.ncbi.nlm.nih.gov/pubmed/34440442
http://dx.doi.org/10.3390/genes12081268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392493/
https://www.ncbi.nlm.nih.gov/pubmed/34440442
http://dx.doi.org/10.3390/genes12081268

Ejemplares similares