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Variants Affecting the C-Terminal Tail of UNC93B1 Are Not a Common Risk Factor for Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a heterogeneous multifactorial disease. Upregulated TLR7 signaling is a known risk factor for SLE. Recently, it was shown that specific genetic variants in UNC93B1 affect the physiological regulation of TLR7 signaling and cause characteristic autoimmune phenotyp...

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Detalles Bibliográficos
Autores principales:	Kiener, Sarah, Ribi, Camillo, Keller, Irene, Chizzolini, Carlo, Trendelenburg, Marten, Huynh-Do, Uyen, von Kempis, Johannes, Leeb, Tosso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392493/ https://www.ncbi.nlm.nih.gov/pubmed/34440442 http://dx.doi.org/10.3390/genes12081268

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