Multiple Sclerosis: Enzymatic Cross Site-Specific Hydrolysis of H1 Histone by IgGs against H1, H2A, H2B, H3, H4 Histones, and Myelin Basic Protein

Histones play a key role in chromatin remodeling and gene transcription. Further, free histones in the blood act as damage-associated molecules. Administration of histones to animals results in systemic inflammatory and toxic effects. Myelin basic protein is the principal constituent element of the...

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Detalles Bibliográficos
Autores principales: Nevinsky, Georgy A., Baranova, Svetlana V., Buneva, Valentina N., Dmitrenok, Pavel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392522/
https://www.ncbi.nlm.nih.gov/pubmed/34439806
http://dx.doi.org/10.3390/biom11081140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392522/
https://www.ncbi.nlm.nih.gov/pubmed/34439806
http://dx.doi.org/10.3390/biom11081140

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