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UPF1: From mRNA Surveillance to Protein Quality Control

Selective recognition and removal of faulty transcripts and misfolded polypeptides are crucial for cell viability. In eukaryotic cells, nonsense-mediated mRNA decay (NMD) constitutes an mRNA surveillance pathway for sensing and degrading aberrant transcripts harboring premature termination codons (P...

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Detalles Bibliográficos
Autores principales: Hwang, Hyun Jung, Park, Yeonkyoung, Kim, Yoon Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392595/
https://www.ncbi.nlm.nih.gov/pubmed/34440199
http://dx.doi.org/10.3390/biomedicines9080995