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Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions

Objective: platelets possess not only haemostatic but also inflammatory properties, which combined are thought to play a detrimental role in thromboinflammatory diseases such as acute coronary syndromes and stroke. Phosphodiesterase (PDE) 3 and -5 inhibitors have demonstrated efficacy in secondary p...

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Detalles Bibliográficos
Autores principales: Coenen, Daniëlle M., Heinzmann, Alexandra C. A., Oggero, Silvia, Albers, Hugo J., Nagy, Magdolna, Hagué, Perrine, Kuijpers, Marijke J. E., Vanderwinden, Jean-Marie, van der Meer, Andries D., Perretti, Mauro, Koenen, Rory R., Cosemans, Judith M. E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392606/
https://www.ncbi.nlm.nih.gov/pubmed/34440764
http://dx.doi.org/10.3390/cells10081998