Small Hexokinase 1 Peptide against Toxic SOD1 G93A Mitochondrial Accumulation in ALS Rescues the ATP-Related Respiration

Mutations in Cu/Zn Superoxide Dismutase (SOD1) gene represent one of the most common causes of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder that specifically affects motor neurons (MNs). The dismutase-active SOD1 G93A mutant is responsible for the formation of toxic aggreg...

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Detalles Bibliográficos
Autores principales: Magrì, Andrea, Risiglione, Pierpaolo, Caccamo, Antonella, Formicola, Beatrice, Tomasello, Marianna Flora, Arrigoni, Cristina, Zimbone, Stefania, Guarino, Francesca, Re, Francesca, Messina, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392704/
https://www.ncbi.nlm.nih.gov/pubmed/34440152
http://dx.doi.org/10.3390/biomedicines9080948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392704/
https://www.ncbi.nlm.nih.gov/pubmed/34440152
http://dx.doi.org/10.3390/biomedicines9080948

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