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Protective Effects of Purple Rice Husk against Diabetic Nephropathy by Modulating PGC-1α/SIRT3/SOD2 Signaling and Maintaining Mitochondrial Redox Equilibrium in Rats

Diabetic nephropathy (DN) is the primary cause of end-stage renal disease worldwide. Oxidative stress and mitochondrial dysfunction are central to its pathogenesis. Rice husk, the leftover from the milling process, is a good source of phytochemicals with antioxidant activity. This study evaluated th...

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Detalles Bibliográficos
Autores principales: Wongmekiat, Orawan, Lailerd, Narissara, Kobroob, Anongporn, Peerapanyasut, Wachirasek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392712/
https://www.ncbi.nlm.nih.gov/pubmed/34439892
http://dx.doi.org/10.3390/biom11081224