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Melatonin restores osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells and alleviates bone loss through the HGF/PTEN/Wnt/β-catenin axis

BACKGROUND: Previous studies reported that melatonin exerts its effect on mesenchymal stem cell (MSC) survival and differentiation into osteogenic and adipogenic lineage. In the current study we aimed to explore the effect of melatonin on osteoporosis and relevant mechanisms. METHODS: Real-time qual...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Jia, Guoliang, Xue, Pan, Li, Zhengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392808/
https://www.ncbi.nlm.nih.gov/pubmed/34457228
http://dx.doi.org/10.1177/2040622321995685