Cargando…

Melatonin restores osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells and alleviates bone loss through the HGF/PTEN/Wnt/β-catenin axis

BACKGROUND: Previous studies reported that melatonin exerts its effect on mesenchymal stem cell (MSC) survival and differentiation into osteogenic and adipogenic lineage. In the current study we aimed to explore the effect of melatonin on osteoporosis and relevant mechanisms. METHODS: Real-time qual...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jun, Jia, Guoliang, Xue, Pan, Li, Zhengwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392808/ https://www.ncbi.nlm.nih.gov/pubmed/34457228 http://dx.doi.org/10.1177/2040622321995685

Ejemplares similares

Catalpol promotes the osteogenic differentiation of bone marrow mesenchymal stem cells via the Wnt/β-catenin pathway
por: Zhu, Yu, et al.
Publicado: (2019)

Raloxifene improves TNF-α-induced osteogenic differentiation inhibition of bone marrow mesenchymal stem cells and alleviates osteoporosis
por: Yang, Fenghe, et al.
Publicado: (2020)

The lncRNA H19/miR-541-3p/Wnt/β-catenin axis plays a vital role in melatonin-mediated osteogenic differentiation of bone marrow mesenchymal stem cells
por: Han, Hui, et al.
Publicado: (2021)

CRYAB promotes osteogenic differentiation of human bone marrow stem cells via stabilizing β‐catenin and promoting the Wnt signalling
por: Zhu, Bin, et al.
Publicado: (2019)

Glycyrrhizic Acid Promotes Osteogenic Differentiation of Human Bone Marrow Stromal Cells by Activating the Wnt/β-Catenin Signaling Pathway
por: Bai, Jinwu, et al.
Publicado: (2021)

ZEB1 Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation Partly via Wnt/β-Catenin Signaling
por: Xu, Cuidi, et al.
Publicado: (2021)

Morusin induces osteogenic differentiation of bone marrow mesenchymal stem cells by canonical Wnt/β-catenin pathway and prevents bone loss in an ovariectomized rat model
por: Chen, Ming, et al.
Publicado: (2021)

Apelin enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly through Wnt/β-catenin signaling pathway
por: Hang, Kai, et al.
Publicado: (2019)

CK1ε drives osteogenic differentiation of bone marrow mesenchymal stem cells via activating Wnt/β-catenin pathway
por: Yu, Zhentang, et al.
Publicado: (2023)

Novel nanocomposite biomaterial to differentiate bone marrow mesenchymal stem cells to the osteogenic lineage for bone restoration
por: Kumar, Arun, et al.
Publicado: (2015)

miR-346 Regulates Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells by Targeting the Wnt/β-Catenin Pathway
por: Wang, Qing, et al.
Publicado: (2013)

Insulin growth factor-1 promotes the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells through the Wnt/β-catenin pathway
por: Feng, Jing, et al.
Publicado: (2021)

Circular RNA Circ_0005564 promotes osteogenic differentiation of bone marrow mesenchymal cells in osteoporosis
por: Liu, Zitao, et al.
Publicado: (2021)

Human bone marrow mesenchymal stem cells-derived exosomes alleviate liver fibrosis through the Wnt/β-catenin pathway
por: Rong, Xiaoli, et al.
Publicado: (2019)

The Multiplicity of Infection-Dependent Effects of Recombinant Adenovirus Carrying HGF Gene on the Proliferation and Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells
por: Wen, Qian, et al.
Publicado: (2018)

Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway
por: Zhang, Wei, et al.
Publicado: (2016)

Knockdown of SERPINB2 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signalling pathway
por: Hang, Kai, et al.
Publicado: (2021)

Neohesperidin promotes the osteogenic differentiation of bone mesenchymal stem cells by activating the Wnt/-catenin signaling pathway
por: Chang, Yue-wen, et al.
Publicado: (2021)

Bone Marrow Adiposity, Bone Mineral Density and Wnt/β-catenin Pathway Inhibitors Levels in Hemodialysis Patients
por: Wang, Yue-Pei, et al.
Publicado: (2022)

MiR-101 Targets the EZH2/Wnt/β-Catenin the Pathway to Promote the Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Wang, Hongrui, et al.
Publicado: (2016)

Knockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/β-catenin signaling pathway
por: Chen, Erman E M, et al.
Publicado: (2017)

Melatonin promotes bone marrow mesenchymal stem cell osteogenic differentiation and prevents osteoporosis development through modulating circ_0003865 that sponges miR-3653-3p
por: Wang, Xudong, et al.
Publicado: (2021)

PHF8 promotes osteogenic differentiation of BMSCs in old rat with osteoporosis by regulating Wnt/β-catenin pathway
por: Pan, Feng, et al.
Publicado: (2022)

Quercetin promotes bone marrow mesenchymal stem cell proliferation and osteogenic differentiation through the H19/miR-625-5p axis to activate the Wnt/β-catenin pathway
por: Bian, Wei, et al.
Publicado: (2021)

Methyl-CpG-binding protein 2 promotes osteogenic differentiation of bone marrow mesenchymal stem cells through regulating forkhead box F1/Wnt/β-Catenin axis
por: Ji, Weiqin, et al.
Publicado: (2021)

Activation of GLP-1 Receptor Promotes Bone Marrow Stromal Cell Osteogenic Differentiation through β-Catenin
por: Meng, Jingru, et al.
Publicado: (2016)

Activation of GLP-1 Receptor Promotes Bone Marrow Stromal Cell Osteogenic Differentiation through β-Catenin
por: Meng, Jingru, et al.
Publicado: (2016)

Wnt/β-catenin signaling mediates the abnormal osteogenic and adipogenic capabilities of bone marrow mesenchymal stem cells from chronic graft-versus-host disease patients
por: Qi, Han-zhou, et al.
Publicado: (2021)

Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression
por: Li, Huiming, et al.
Publicado: (2019)

BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling
por: Zuo, Rui, et al.
Publicado: (2019)

Qualitative Aspects of Bone Marrow Adiposity in Osteoporosis
por: Pino, Ana María, et al.
Publicado: (2016)

Melatonin Inhibits Osteoclastogenesis and Osteolytic Bone Metastasis: Implications for Osteoporosis
por: MacDonald, Iona J., et al.
Publicado: (2021)

Circ_0067680 expedites the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells through miR-4429/CTNNB1/Wnt/β-catenin pathway
por: Huang, Yuansheng, et al.
Publicado: (2021)

Mechanism of miRNA-31 Regulating Wnt/β-catenin Signaling Pathway by Targeting Satb2 in the Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Ouyang, Xiao, et al.
Publicado: (2023)

Toxoplasma gondii excretory/secretory proteins promotes osteogenic differentiation of bone marrow mesenchymal stem cells via aerobic glycolysis mediated by Wnt/β-catenin signaling pathway
por: Zhan, Weiqiang, et al.
Publicado: (2023)

Vitamin D Alleviates Cadmium-Induced Inhibition of Chicken Bone Marrow Stromal Cells’ Osteogenic Differentiation In Vitro
por: Tong, Xishuai, et al.
Publicado: (2023)

HGF Expressing Stem Cells in Usual Interstitial Pneumonia Originate from the Bone Marrow and Are Antifibrotic
por: Gazdhar, Amiq, et al.
Publicado: (2013)

TLR4 Activation Promotes Bone Marrow MSC Proliferation and Osteogenic Differentiation via Wnt3a and Wnt5a Signaling
por: He, Xiaoqing, et al.
Publicado: (2016)

Bone Progenitors Produced by Direct Osteogenic Differentiation of the Unprocessed Bone Marrow Demonstrate High Osteogenic Potential In Vitro and In Vivo
por: Ginis, Irene, et al.
Publicado: (2012)

Correction to: BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling
por: Zuo, Rui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_muov42fnacgf2f06cvnh7nqnqd