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Calpain-Mediated Mitochondrial Damage: An Emerging Mechanism Contributing to Cardiac Disease

Calpains belong to the family of calcium-dependent cysteine proteases expressed ubiquitously in mammals and many other organisms. Activation of calpain is observed in diseased hearts and is implicated in cardiac cell death, hypertrophy, fibrosis, and inflammation. However, the underlying mechanisms...

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Detalles Bibliográficos
Autores principales: Zhang, Mengxiao, Wang, Grace, Peng, Tianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392834/
https://www.ncbi.nlm.nih.gov/pubmed/34440793
http://dx.doi.org/10.3390/cells10082024