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Calpain-Mediated Mitochondrial Damage: An Emerging Mechanism Contributing to Cardiac Disease
Calpains belong to the family of calcium-dependent cysteine proteases expressed ubiquitously in mammals and many other organisms. Activation of calpain is observed in diseased hearts and is implicated in cardiac cell death, hypertrophy, fibrosis, and inflammation. However, the underlying mechanisms...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392834/ https://www.ncbi.nlm.nih.gov/pubmed/34440793 http://dx.doi.org/10.3390/cells10082024 |