Therapeutic Potential of PARP Inhibitors in the Treatment of Gastrointestinal Cancers

Gastrointestinal (GI) malignancies are a major global health burden, with high mortality rates. The identification of novel therapeutic strategies is crucial to improve treatment and survival of patients. The poly (ADP-ribose) polymerase (PARP) enzymes involved in the DNA damage response (DDR) play...

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Detalles Bibliográficos
Autores principales: Alhusaini, Abdullah, Cannon, Aoife, Maher, Stephen G., Reynolds, John V., Lynam-Lennon, Niamh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392860/
https://www.ncbi.nlm.nih.gov/pubmed/34440228
http://dx.doi.org/10.3390/biomedicines9081024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392860/
https://www.ncbi.nlm.nih.gov/pubmed/34440228
http://dx.doi.org/10.3390/biomedicines9081024

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