Anthraquinones as Inhibitors of SOS RAS-GEF Activity

Recent breakthroughs have reignited interest in RAS GEFs as direct therapeutic targets. To search for new inhibitors of SOS GEF activity, a repository of known/approved compounds (NIH-NACTS) and a library of new marine compounds (Biomar Microbial Technologies) were screened by means of in vitro RAS-...

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Detalles Bibliográficos
Autores principales: Fernández-Medarde, Alberto, Fuentes-Mateos, Rocío, García-Navas, Rósula, Juan, Andrea Olarte-San, Sánchez-López, José María, Fernández-Medarde, Antonio, Santos, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392861/
https://www.ncbi.nlm.nih.gov/pubmed/34439794
http://dx.doi.org/10.3390/biom11081128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392861/
https://www.ncbi.nlm.nih.gov/pubmed/34439794
http://dx.doi.org/10.3390/biom11081128

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