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Mechanism of Human Telomerase Reverse Transcriptase (hTERT) Regulation and Clinical Impacts in Leukemia

The proliferative capacity and continuous survival of cells are highly dependent on telomerase expression and the maintenance of telomere length. For this reason, elevated expression of telomerase has been identified in virtually all cancers, including leukemias; however, it should be noted that exp...

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Detalles Bibliográficos
Autores principales: Yik, Mot Yee, Azlan, Adam, Rajasegaran, Yaashini, Rosli, Aliaa, Yusoff, Narazah Mohd, Moses, Emmanuel Jairaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392866/
https://www.ncbi.nlm.nih.gov/pubmed/34440361
http://dx.doi.org/10.3390/genes12081188