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IL7-Fc Enhances the Efficacy of Adoptive T Cell Therapy under Lymphopenic Conditions in a Murine Melanoma Model

Adoptive cell therapy (ACT) using tumor-reactive T cells is a promising form of immunotherapy to specifically target cancer. However, the survival and functional maintenance of adoptively transferred T cells remains a challenge, ultimately limiting their efficacy. Here, we evaluated the use of recom...

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Detalles Bibliográficos
Autores principales: Yu, Eun M., Cho, Eunjung, Singh, Rohit, Kim, Seon-Hee, Han, Chungyong, Han, Seongeun, Lee, Don G., Kim, Young H., Kwon, Byoung S., Choi, Beom K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392867/
https://www.ncbi.nlm.nih.gov/pubmed/34440787
http://dx.doi.org/10.3390/cells10082018