Novel Polyethylene Glycol-Conjugated Triazole Derivative with High Thyrointegrin αvβ3 Affinity in Acute Myeloid Leukemia Management

SIMPLE SUMMARY: The integrin αvβ3 antagonist (P-bi-TAT) is associated with the downregulation of signaling pathways, especially NF-κB pathway, which play an important role in leukemogenesis. Our results provide a rationale for further evaluation of the αvβ3 antagonists as providing potential therape...

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Detalles Bibliográficos
Autores principales: Sudha, Thangirala, Godugu, Kavitha, Darwish, Noureldien H. E., Nazeer, Tipu, Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392871/
https://www.ncbi.nlm.nih.gov/pubmed/34439224
http://dx.doi.org/10.3390/cancers13164070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392871/
https://www.ncbi.nlm.nih.gov/pubmed/34439224
http://dx.doi.org/10.3390/cancers13164070

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