Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription

[Image: see text] Dysregulation of the transcription factor MYC is involved in many human cancers. The dimeric transcription factor complexes of MYC/MAX and MAX/MAX activate or inhibit, respectively, gene transcription upon binding to the same enhancer box DNA. Targeting these complexes in cancer is...

Descripción completa

Detalles Bibliográficos
Autores principales: Pomplun, Sebastian, Jbara, Muhammad, Schissel, Carly K., Wilson Hawken, Susana, Boija, Ann, Li, Charles, Klein, Isaac, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393199/
https://www.ncbi.nlm.nih.gov/pubmed/34471684
http://dx.doi.org/10.1021/acscentsci.1c00663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393199/
https://www.ncbi.nlm.nih.gov/pubmed/34471684
http://dx.doi.org/10.1021/acscentsci.1c00663

Ejemplares similares