Modulation of Siglec-7 Signaling Via In Situ-Created High-Affinity cis-Ligands

[Image: see text] Sialic acid-binding immunoglobulin-like lectins, also known as Siglecs, have recently been designated as glyco-immune checkpoints. Through their interactions with sialylated glycan ligands overexpressed on tumor cells, inhibitory Siglecs on innate and adaptive immune cells modulate...

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Detalles Bibliográficos
Autores principales: Hong, Senlian, Yu, Chenhua, Rodrigues, Emily, Shi, Yujie, Chen, Hongmin, Wang, Peng, Chapla, Digantkumar G., Gao, Tao, Zhuang, Ruoxuan, Moremen, Kelley W., Paulson, James C., Macauley, Matthew S., Wu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393205/
https://www.ncbi.nlm.nih.gov/pubmed/34471678
http://dx.doi.org/10.1021/acscentsci.1c00064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393205/
https://www.ncbi.nlm.nih.gov/pubmed/34471678
http://dx.doi.org/10.1021/acscentsci.1c00064

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