The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner

The Cx43 carboxyl-terminus (CT) mimetic peptide, αCT1, originally designed to bind to Zonula Occludens 1 (ZO1) and thereby inhibit Cx43/ZO1 interaction, was used as a tool to probe the role of Cx43/ZO1 association in regulation of epithelial/endothelial barrier function. Using both in vitro and ex v...

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Detalles Bibliográficos
Autores principales: Strauss, Randy E., Mezache, Louisa, Veeraraghavan, Rengasayee, Gourdie, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393261/
https://www.ncbi.nlm.nih.gov/pubmed/34439858
http://dx.doi.org/10.3390/biom11081192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393261/
https://www.ncbi.nlm.nih.gov/pubmed/34439858
http://dx.doi.org/10.3390/biom11081192

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