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Angiotensin-converting enzyme 2 alleviates pulmonary artery hypertension through inhibition of focal adhesion kinase expression

Focal adhesion kinase (FAK) is an important therapeutic target in pulmonary artery hypertension (PAH); however, the mechanism of its activation remains unknown. The present study aimed to investigate whether angiotensin-converting enzyme 2 (ACE2) could regulate FAK and alleviate PAH in a rat model o...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Xu, Jingjing, Wu, Jinbo, Gao, Shunheng, Wang, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393266/
https://www.ncbi.nlm.nih.gov/pubmed/34504610
http://dx.doi.org/10.3892/etm.2021.10599