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Clinically Applicable Cyclotron-Produced Gallium-68 Gives High-Yield Radiolabeling of DOTA-Based Tracers

By using solid targets in medical cyclotrons, it is possible to produce large amounts of (68)GaCl(3). Purification of Ga(3+) from metal ion impurities is a critical step, as these metals compete with Ga(3+) in the complexation with different chelators, which negatively affects the radiolabeling yiel...

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Detalles Bibliográficos
Autores principales: Jussing, Emma, Milton, Stefan, Samén, Erik, Moein, Mohammad Mahdi, Bylund, Lovisa, Axelsson, Rimma, Siikanen, Jonathan, Tran, Thuy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393313/
https://www.ncbi.nlm.nih.gov/pubmed/34439784
http://dx.doi.org/10.3390/biom11081118