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Clinically Applicable Cyclotron-Produced Gallium-68 Gives High-Yield Radiolabeling of DOTA-Based Tracers
By using solid targets in medical cyclotrons, it is possible to produce large amounts of (68)GaCl(3). Purification of Ga(3+) from metal ion impurities is a critical step, as these metals compete with Ga(3+) in the complexation with different chelators, which negatively affects the radiolabeling yiel...
Autores principales: | Jussing, Emma, Milton, Stefan, Samén, Erik, Moein, Mohammad Mahdi, Bylund, Lovisa, Axelsson, Rimma, Siikanen, Jonathan, Tran, Thuy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393313/ https://www.ncbi.nlm.nih.gov/pubmed/34439784 http://dx.doi.org/10.3390/biom11081118 |
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