Coat Color-Facilitated Efficient Generation and Analysis of a Mouse Model of Down Syndrome Triplicated for All Human Chromosome 21 Orthologous Regions

Down syndrome (DS) is one of the most complex genetic disorders in humans and a leading genetic cause of developmental delays and intellectual disabilities. The mouse remains an essential model organism in DS research because human chromosome 21 (Hsa21) is orthologously conserved with three regions...

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Detalles Bibliográficos
Autores principales: Li, Yichen, Xing, Zhuo, Yu, Tao, Pao, Annie, Daadi, Marcel, Yu, Y. Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393392/
https://www.ncbi.nlm.nih.gov/pubmed/34440389
http://dx.doi.org/10.3390/genes12081215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393392/
https://www.ncbi.nlm.nih.gov/pubmed/34440389
http://dx.doi.org/10.3390/genes12081215

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