siRNA Mediate RNA Interference Concordant with Early On-Target Transient Transcriptional Interference

Exogenous siRNAs are commonly used to regulate endogenous gene expression levels for gene function analysis, genotype–phenotype association studies and for gene therapy. Exogenous siRNAs can target mRNAs within the cytosol as well as nascent RNA transcripts within the nucleus, thus complicating siRN...

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Detalles Bibliográficos
Autores principales: Fang, Zhiming, Zhao, Zhongming, Eapen, Valsamma, Clarke, Raymond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393430/
https://www.ncbi.nlm.nih.gov/pubmed/34440463
http://dx.doi.org/10.3390/genes12081290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393430/
https://www.ncbi.nlm.nih.gov/pubmed/34440463
http://dx.doi.org/10.3390/genes12081290

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