Precise Epigenetic Analysis Using Targeted Bisulfite Genomic Sequencing Distinguishes FSHD1, FSHD2, and Healthy Subjects

The true prevalence of facioscapulohumeral muscular dystrophy (FSHD) is unknown due to difficulties with accurate clinical evaluation and the complexities of current genetic diagnostics. Interestingly, all forms of FSHD are linked to epigenetic changes in the chromosome 4q35 D4Z4 macrosatellite, sug...

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Detalles Bibliográficos
Autores principales: Gould, Taylor, Jones, Takako I., Jones, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393475/
https://www.ncbi.nlm.nih.gov/pubmed/34441403
http://dx.doi.org/10.3390/diagnostics11081469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393475/
https://www.ncbi.nlm.nih.gov/pubmed/34441403
http://dx.doi.org/10.3390/diagnostics11081469

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