Long non-coding RNA CASC2 restrains high glucose-induced proliferation, inflammation and fibrosis in human glomerular mesangial cells through mediating miR-135a-5p/TIMP3 axis and JNK signaling

BACKGROUND: Diabetic nephropathy (DN) is a common complication of diabetes. Long non-coding RNA (lncRNA) cancer susceptibility candidate 2 (CASC2) is reported to exert a protective role in DN by a previous study. The working mechanism underlying the protective role of CASC2 in DN progression was fur...

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Detalles Bibliográficos
Autores principales: Zhu, Dongju, Wu, Xiang, Xue, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393478/
https://www.ncbi.nlm.nih.gov/pubmed/34446088
http://dx.doi.org/10.1186/s13098-021-00709-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393478/
https://www.ncbi.nlm.nih.gov/pubmed/34446088
http://dx.doi.org/10.1186/s13098-021-00709-5

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