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Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving progressive degeneration of upper and lower motor neurons. The pattern of lower motor neuron loss along the spinal cord follows the pattern of deposition of phosphorylated TDP-43 aggregates. The blood-spinal cord barr...

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Detalles Bibliográficos
Autores principales: Waters, Sarah, Swanson, Molly E. V., Dieriks, Birger V., Zhang, Yibin B., Grimsey, Natasha L., Murray, Helen C., Turner, Clinton, Waldvogel, Henry J., Faull, Richard L. M., An, Jiyan, Bowser, Robert, Curtis, Maurice A., Dragunow, Mike, Scotter, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393479/
https://www.ncbi.nlm.nih.gov/pubmed/34446086
http://dx.doi.org/10.1186/s40478-021-01244-0