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Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving progressive degeneration of upper and lower motor neurons. The pattern of lower motor neuron loss along the spinal cord follows the pattern of deposition of phosphorylated TDP-43 aggregates. The blood-spinal cord barr...
Autores principales: | Waters, Sarah, Swanson, Molly E. V., Dieriks, Birger V., Zhang, Yibin B., Grimsey, Natasha L., Murray, Helen C., Turner, Clinton, Waldvogel, Henry J., Faull, Richard L. M., An, Jiyan, Bowser, Robert, Curtis, Maurice A., Dragunow, Mike, Scotter, Emma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393479/ https://www.ncbi.nlm.nih.gov/pubmed/34446086 http://dx.doi.org/10.1186/s40478-021-01244-0 |
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