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Genome-wide profiling of alternative splicing in glioblastoma and their clinical value

BACKGROUND: Alternative splicing (AS), one of the main post-transcriptional biological regulation mechanisms, plays a key role in the progression of glioblastoma (GBM). Systematic AS profiling in GBM is limited and urgently needed. METHODS: TCGA SpliceSeq data and the corresponding clinical data wer...

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Detalles Bibliográficos
Autores principales: Li, Youwei, Guo, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393481/
https://www.ncbi.nlm.nih.gov/pubmed/34445990
http://dx.doi.org/10.1186/s12885-021-08681-z