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S1P Increases VEGF Production in Osteoblasts and Facilitates Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-16-5p Expression via the c-Src/FAK Signaling Pathway in Rheumatoid Arthritis

Angiogenesis is a critical process in the formation of new capillaries and a key participant in rheumatoid arthritis (RA) pathogenesis. Vascular endothelial growth factor (VEGF) stimulation of endothelial progenitor cells (EPCs) facilitates angiogenesis and the progression of RA. Phosphorylation of...

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Detalles Bibliográficos
Autores principales: Huang, Chien-Chung, Tseng, Tzu-Ting, Liu, Shan-Chi, Lin, Yen-You, Law, Yat-Yin, Hu, Sung-Lin, Wang, Shih-Wei, Tsai, Chun-Hao, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393529/
https://www.ncbi.nlm.nih.gov/pubmed/34440937
http://dx.doi.org/10.3390/cells10082168