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Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations

Machine learning methods applied to large genomic datasets (such as those used in GWAS) have led to the creation of polygenic risk scores (PRSs) that can be used identify individuals who are at highly elevated risk for important disease conditions, such as coronary artery disease (CAD), diabetes, hy...

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Detalles Bibliográficos
Autores principales: Tellier, Laurent C. A. M., Eccles, Jennifer, Treff, Nathan R., Lello, Louis, Fishel, Simon, Hsu, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393569/
https://www.ncbi.nlm.nih.gov/pubmed/34440279
http://dx.doi.org/10.3390/genes12081105