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Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations
Machine learning methods applied to large genomic datasets (such as those used in GWAS) have led to the creation of polygenic risk scores (PRSs) that can be used identify individuals who are at highly elevated risk for important disease conditions, such as coronary artery disease (CAD), diabetes, hy...
Autores principales: | Tellier, Laurent C. A. M., Eccles, Jennifer, Treff, Nathan R., Lello, Louis, Fishel, Simon, Hsu, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393569/ https://www.ncbi.nlm.nih.gov/pubmed/34440279 http://dx.doi.org/10.3390/genes12081105 |
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