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Exploring the Interplay of Telomerase Reverse Transcriptase and β-Catenin in Hepatocellular Carcinoma

SIMPLE SUMMARY: Liver cancer is one of the deadliest human cancers. Two of the most common molecular aberrations in liver cancer are: (1) activating mutations in the gene encoding β-catenin (CTNNB1); and (2) promoter mutations in telomerase reverse transcriptase (TERT). Here, we review recent findin...

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Detalles Bibliográficos
Autores principales: Kotiyal, Srishti, Evason, Kimberley Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393605/
https://www.ncbi.nlm.nih.gov/pubmed/34439356
http://dx.doi.org/10.3390/cancers13164202