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Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2

SARS-CoV-2 infection of host cells is driven by binding of the SARS-CoV-2 spike-(S)-protein to lung type II pneumocytes, followed by virus replication. Surfactant protein SP-D, member of the front-line immune defense of the lungs, binds glycosylated structures on invading pathogens such as viruses t...

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Detalles Bibliográficos
Autores principales: Arroyo, Raquel, Grant, Shawn N., Colombo, Miriam, Salvioni, Lucia, Corsi, Fabio, Truffi, Marta, Ottolina, Davide, Hurst, Brett, Salzberg, Marc, Prosperi, Davide, Kingma, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393632/
https://www.ncbi.nlm.nih.gov/pubmed/34439781
http://dx.doi.org/10.3390/biom11081114