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Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2
SARS-CoV-2 infection of host cells is driven by binding of the SARS-CoV-2 spike-(S)-protein to lung type II pneumocytes, followed by virus replication. Surfactant protein SP-D, member of the front-line immune defense of the lungs, binds glycosylated structures on invading pathogens such as viruses t...
Autores principales: | Arroyo, Raquel, Grant, Shawn N., Colombo, Miriam, Salvioni, Lucia, Corsi, Fabio, Truffi, Marta, Ottolina, Davide, Hurst, Brett, Salzberg, Marc, Prosperi, Davide, Kingma, Paul S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393632/ https://www.ncbi.nlm.nih.gov/pubmed/34439781 http://dx.doi.org/10.3390/biom11081114 |
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