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Bacitracin and Rutin Regulate Tissue Factor Production in Inflammatory Monocytes and Acute Myeloid Leukemia Blasts

SIMPLE SUMMARY: Aberrant tissue factor (TF) expression by transformed myeloblasts and inflammatory monocytes contributes to coagulation activation in acute myeloid leukemia (AML). TF procoagulant activity (PCA) is regulated by protein disulfide isomerase (PDI), an oxidoreductase with chaperone activ...

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Detalles Bibliográficos
Autores principales: Beckmann, Lennart, Rolling, Christina Charlotte, Voigtländer, Minna, Mäder, Jonathan, Klingler, Felix, Schulenkorf, Anita, Lehr, Carina, Bokemeyer, Carsten, Ruf, Wolfram, Langer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393688/
https://www.ncbi.nlm.nih.gov/pubmed/34439096
http://dx.doi.org/10.3390/cancers13163941