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Bacitracin and Rutin Regulate Tissue Factor Production in Inflammatory Monocytes and Acute Myeloid Leukemia Blasts
SIMPLE SUMMARY: Aberrant tissue factor (TF) expression by transformed myeloblasts and inflammatory monocytes contributes to coagulation activation in acute myeloid leukemia (AML). TF procoagulant activity (PCA) is regulated by protein disulfide isomerase (PDI), an oxidoreductase with chaperone activ...
Autores principales: | Beckmann, Lennart, Rolling, Christina Charlotte, Voigtländer, Minna, Mäder, Jonathan, Klingler, Felix, Schulenkorf, Anita, Lehr, Carina, Bokemeyer, Carsten, Ruf, Wolfram, Langer, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393688/ https://www.ncbi.nlm.nih.gov/pubmed/34439096 http://dx.doi.org/10.3390/cancers13163941 |
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